Burkholderia pseudomallei K96243, BPSS0307

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0307
Name
Replicon chromosome 2
Genomic location 423325 - 424737 (- strand)

Cross-References

RefSeq YP_110327.1
GI 53721342
Entrez 3096346
GI 53721342
INSDC CAH37755.1
NCBI Locus Tag BPSS0307
RefSeq YP_110327.1,GeneID
UniParc UPI000043B880
UniProtKB Acc Q63NJ2
UniProtKB ID Q63NJ2_BURPS
UniRef100 UniRef100_Q63NJ2
UniRef50 UniRef50_Q8ZPC9
UniRef90 UniRef90_Q2T3G9

Product

Feature Type CDS
Coding Frame 1
Product Name
gamma-aminobutyraldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -0.53
Kyte-Doolittle Hydrophobicity Value 0.070
Molecular Weight (kDa) 49428.7
Isoelectric Point (pI) 6.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG016377 (377 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0307

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-77
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-77
Percent Identity: 36.7
Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 1 family member A2 [Source:HGNC Symbol;Acc:HGNC:15472]
E-value: 8.1e-77
Percent Identity: 36.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268