Burkholderia pseudomallei K96243, BPSS0086

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSS0086
Name
Replicon chromosome 2
Genomic location 99533 - 101128 (- strand)

Cross-References

RefSeq YP_110109.1
GI 53721124
Entrez 3094976
GI 53721124
INSDC CAH37532.1
NCBI Locus Tag BPSS0086
RefSeq YP_110109.1,GeneID
UniParc UPI000043B7A8
UniProtKB Acc Q63P60
UniProtKB ID Q63P60_BURPS
UniRef100 UniRef100_Q63P60
UniRef50 UniRef50_G9IJE1
UniRef90 UniRef90_A0A069BA68

Product

Feature Type CDS
Coding Frame 1
Product Name
cytochrome C oxidase-related protein
Synonyms
Evidence for Translation
Charge (pH 7) 9.03
Kyte-Doolittle Hydrophobicity Value 0.611
Molecular Weight (kDa) 59244.6
Isoelectric Point (pI) 9.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 420 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG020397 (285 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS0086

Human Homologs

Ensembl 97, assembly GRCh38.p12
mitochondrially encoded cytochrome c oxidase I [Source:HGNC Symbol;Acc:HGNC:7419]
E-value: 1.8e-141
Percent Identity: 48.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268