Burkholderia pseudomallei K96243, BPSL3426

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3426
Name
Replicon chromosome 1
Genomic location 4067752 - 4068444 (+ strand)

Cross-References

RefSeq YP_110019.1
GI 53721033
Entrez 3093752
GI 53721033
INSDC CAH37438.1
NCBI Locus Tag BPSL3426
RefSeq YP_110019.1,GeneID
UniParc UPI000043B74E
UniProtKB Acc Q63PF0
UniProtKB ID Q63PF0_BURPS
UniRef100 UniRef100_Q2STB8
UniRef50 UniRef50_Q0K5I4
UniRef90 UniRef90_Q2STB8

Product

Feature Type CDS
Coding Frame 1
Product Name
two-component response regulator
Synonyms
Evidence for Translation
Charge (pH 7) -1.10
Kyte-Doolittle Hydrophobicity Value -0.243
Molecular Weight (kDa) 25947.6
Isoelectric Point (pI) 6.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 619 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000061 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3426

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268