Burkholderia pseudomallei K96243, BPSL3396 (atpD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3396
Name
atpD
Replicon chromosome 1
Genomic location 4034643 - 4036037 (- strand)

Cross-References

RefSeq YP_109989.1
GI 53721003
Entrez 3093524
GI 53721003
INSDC CAH37408.1
NCBI Locus Tag BPSL3396
RefSeq YP_109989.1,GeneID
UniParc UPI000043B730
UniProtKB Acc Q63PI0
UniProtKB ID ATPB1_BURPS
UniRef100 UniRef100_A3MQJ9
UniRef50 UniRef50_P50002
UniRef90 UniRef90_Q13SQ2

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP synthase F0F1 subunit beta
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (48.4 kDa, pI 5.13, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (48.4 kDa, pI 5.08, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (48.2 kDa, pI 4.95, PMID:21960737)
Charge (pH 7) -11.17
Kyte-Doolittle Hydrophobicity Value -0.126
Molecular Weight (kDa) 50622.6
Isoelectric Point (pI) 5.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4Q4L HYDROLASE 04/14/14 Crystal structure of an ATP synthase subunit beta 1 (F1-B1) from Burkholderia thailandensis BURKHOLDERIA THAILANDENSIS 2.2 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 666 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000092 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3396
Search term: atpD

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP synthase F1 subunit beta [Source:HGNC Symbol;Acc:HGNC:830]
E-value: 1.6e-181
Percent Identity: 69.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268