Burkholderia pseudomallei K96243, BPSL3336

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3336
Name
Replicon chromosome 1
Genomic location 3955731 - 3956408 (- strand)

Cross-References

RefSeq YP_109932.1
GI 53720946
Entrez 3091784
GI 53720946
INSDC CAH37349.1
NCBI Locus Tag BPSL3336
RefSeq YP_109932.1,GeneID
UniParc UPI000043B6F7
UniProtKB Acc Q63PN7
UniProtKB ID Q63PN7_BURPS
UniRef100 UniRef100_A0A097XYV7
UniRef50 UniRef50_Q7DDH4
UniRef90 UniRef90_Q2STP9

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) 3.17
Kyte-Doolittle Hydrophobicity Value -0.082
Molecular Weight (kDa) 23672.7
Isoelectric Point (pI) 9.06

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 59 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005600 (598 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3336
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268