Burkholderia pseudomallei K96243, BPSL3320 (fliD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3320
Name
fliD
Replicon chromosome 1
Genomic location 3938991 - 3940511 (+ strand)

Cross-References

RefSeq YP_109916.1
GI 53720930
Entrez 3094016
GI 53720930
INSDC CAH37333.1
NCBI Locus Tag BPSL3320
RefSeq YP_109916.1,GeneID
UniParc UPI000043B6E7
UniProtKB Acc Q63PQ3
UniProtKB ID Q63PQ3_BURPS
UniRef100 UniRef100_A0A095SS50
UniRef50 UniRef50_A1V924
UniRef90 UniRef90_A1V924

Product

Feature Type CDS
Coding Frame 1
Product Name
flagellar hook-associated protein
Synonyms
Evidence for Translation
Charge (pH 7) -0.78
Kyte-Doolittle Hydrophobicity Value 0.095
Molecular Weight (kDa) 49698.1
Isoelectric Point (pI) 5.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Extracellular Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0430
Category Flagella
Evidence ECO:0000314
direct assay evidence used in manual assertion
Host Organism
Notes
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 239 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000147 (722 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3320
Search term: fliD

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268