Burkholderia pseudomallei K96243, BPSL3242

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3242
Name
Replicon chromosome 1
Genomic location 3851722 - 3853992 (- strand)

Cross-References

RefSeq YP_109836.1
GI 53720850
Entrez 3091568
GI 53720850
INSDC CAH37253.1
NCBI Locus Tag BPSL3242
RefSeq YP_109836.1,GeneID
UniParc UPI000043B69A
UniProtKB Acc Q63PY2
UniProtKB ID Q63PY2_BURPS
UniRef100 UniRef100_Q3JYB6
UniRef50 UniRef50_P76558
UniRef90 UniRef90_A9AD90

Product

Feature Type CDS
Coding Frame 1
Product Name
malic enzyme
Synonyms
Evidence for Translation
Charge (pH 7) -6.17
Kyte-Doolittle Hydrophobicity Value 0.057
Molecular Weight (kDa) 80790.6
Isoelectric Point (pI) 6.22

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000228 (1552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3242
Search term: malic enzyme

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268