Burkholderia pseudomallei K96243, BPSL3226 (nusG)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL3226
Name	nusG
Replicon	chromosome 1
Genomic location	3827427 - 3827984 (- strand)

Cross-References

RefSeq	YP_109820.1
GI	53720834
Entrez	3094405
GI	53720834
INSDC	CAH37237.1
NCBI Locus Tag	BPSL3226
RefSeq	YP_109820.1,GeneID
UniParc	UPI000043B68B
UniProtKB Acc	Q63PZ8
UniProtKB ID	Q63PZ8_BURPS
UniRef100	UniRef100_A0A069B595
UniRef50	UniRef50_Q01SW9
UniRef90	UniRef90_A1V8B7

Product

Feature Type	CDS
Coding Frame	1
Product Name	transcription antitermination protein NusG
Synonyms
Evidence for Translation
Charge (pH 7)	0.72
Kyte-Doolittle Hydrophobicity Value	-0.510
Molecular Weight (kDa)	20920.9
Isoelectric Point (pI)	7.77

Subcellular localization

Individual Mappings	Localization Confidence PMID Extracellular Class 1 quantitative mass spectrometry evidence 25635268 Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000245 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL3226 Search term: nusG Search term: transcription antitermination protein NusG

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants. Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM Mol Cell Proteomics 2015 Apr;14(4):905-16 PubMed ID: 25635268