Burkholderia pseudomallei K96243, BPSL3224 (rplA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3224
Name
rplA
Replicon chromosome 1
Genomic location 3826151 - 3826849 (- strand)

Cross-References

RefSeq YP_109818.1
GI 53720832
Entrez 3094104
GI 53720832
INSDC CAH37235.1
NCBI Locus Tag BPSL3224
RefSeq YP_109818.1,GeneID
UniParc UPI000043B689
UniProtKB Acc Q63Q00
UniProtKB ID RL1_BURPS
UniRef100 UniRef100_A3MRU2
UniRef50 UniRef50_Q9RSS8
UniRef90 UniRef90_B2JIH7

Product

Feature Type CDS
Coding Frame 1
Product Name
50S ribosomal protein L1
Synonyms
Evidence for Translation
Charge (pH 7) 9.20
Kyte-Doolittle Hydrophobicity Value 0.023
Molecular Weight (kDa) 24321.0
Isoelectric Point (pI) 10.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 663 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000247 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3224
Search term: rplA

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268