Burkholderia pseudomallei K96243, BPSL3222 (rplL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3222
Name
rplL
Replicon chromosome 1
Genomic location 3824918 - 3825250 (- strand)

Cross-References

RefSeq YP_109816.1
GI 53720830
Entrez 3093065
GI 53720830
INSDC CAH37233.1
NCBI Locus Tag BPSL3222
RefSeq YP_109816.1,GeneID
UniParc UPI0000440F59
UniProtKB Acc Q63Q02
UniProtKB ID RL7_BURPS
UniRef100 UniRef100_A3MRU4
UniRef50 UniRef50_P07472
UniRef90 UniRef90_Q2SU18

Product

Feature Type CDS
Coding Frame 1
Product Name
50S ribosomal protein L7/L12
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (12.6 kDa, pI 4.90, PMID:21960737)
Charge (pH 7) -3.00
Kyte-Doolittle Hydrophobicity Value 0.045
Molecular Weight (kDa) 11146.7
Isoelectric Point (pI) 4.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000249 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3222
Search term: rplL

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268