Burkholderia pseudomallei K96243, BPSL3213 (rplC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL3213
Name
rplC
Replicon chromosome 1
Genomic location 3808136 - 3808795 (- strand)

Cross-References

RefSeq YP_109807.1
GI 53720821
Entrez 3091930
GI 53720821
INSDC CAH37224.1
NCBI Locus Tag BPSL3213
RefSeq YP_109807.1,GeneID
UniParc UPI000043B67F
UniProtKB Acc Q63Q11
UniProtKB ID RL3_BURPS
UniRef100 UniRef100_A3P0B3
UniRef50 UniRef50_A2SLF7
UniRef90 UniRef90_Q2SU27

Product

Feature Type CDS
Coding Frame 1
Product Name
50S ribosomal protein L3
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (24.5 kDa, pI 4.24, PMID:21960737)
Charge (pH 7) 11.95
Kyte-Doolittle Hydrophobicity Value -0.170
Molecular Weight (kDa) 22967.3
Isoelectric Point (pI) 10.69

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 599 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000257 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3213
Search term: rplC

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268