Burkholderia pseudomallei K96243, BPSL3102 (tssG-1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL3102
Name
tssG-1
Replicon chromosome 1
Genomic location 3707119 - 3708219 (- strand)
CommentGene is part of a cluster known as the type VI secretion system gene cluster tss-1 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-1 cluster later (PMID:22007185)

Cross-References

RefSeq YP_109697.1
GI 53720711
Entrez 3093361
GI 53720711
INSDC CAH37113.1
NCBI Locus Tag BPSL3102
RefSeq YP_109697.1,GeneID
UniParc UPI000043B618
UniProtKB Acc Q63QC1
UniProtKB ID Q63QC1_BURPS
UniRef100 UniRef100_A0A069B4W7
UniRef50 UniRef50_A0A0B6RV29
UniRef90 UniRef90_Q2SUD3

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system protein TssG-1
Product Name Confidence: Class 2
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 3.39
Kyte-Doolittle Hydrophobicity Value -0.186
Molecular Weight (kDa) 41027.3
Isoelectric Point (pI) 8.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 103 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000371 (648 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL3102
Search term: tssG-1

References

In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS.
Microbiology. 2007 Aug;153(Pt 8):2689-99.
PubMed ID: 17660433
PubMed ID: 22007185
Type VI secretion is a major virulence determinant in Burkholderia mallei.
Schell MA(1), Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D.
Mol Microbiol. 2007 Jun;64(6):1466-85.
PubMed ID: 17555434