Burkholderia pseudomallei K96243, BPSL2749

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2749
Name
Replicon chromosome 1
Genomic location 3291992 - 3292294 (+ strand)

Cross-References

RefSeq YP_109345.1
GI 53720359
Entrez 3091892
GI 53720359
INSDC CAH36757.1
NCBI Locus Tag BPSL2749
RefSeq YP_109345.1,GeneID
UniParc UPI000043B4CC
UniProtKB Acc Q63RC3
UniProtKB ID Q63RC3_BURPS
UniRef100 UniRef100_A0A097Y172
UniRef50 UniRef50_Q8Y1D7
UniRef90 UniRef90_A2S9K9

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 2.47
Kyte-Doolittle Hydrophobicity Value -0.286
Molecular Weight (kDa) 10839.4
Isoelectric Point (pI) 9.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 74 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000674 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2749

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268