Burkholderia pseudomallei K96243, BPSL2715

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2715
Name
Replicon chromosome 1
Genomic location 3246675 - 3248522 (- strand)

Cross-References

RefSeq YP_109311.1
GI 53720325
Entrez 3092215
GI 53720325
INSDC CAH36723.1
NCBI Locus Tag BPSL2715
RefSeq YP_109311.1,GeneID
UniParc UPI000043B4AA
UniProtKB Acc Q63RF7
UniProtKB ID Q63RF7_BURPS
UniRef100 UniRef100_Q63RF7
UniRef50 UniRef50_Q8Y0P0
UniRef90 UniRef90_Q63RF7

Product

Feature Type CDS
Coding Frame 1
Product Name
lipoprotein
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) -4.15
Kyte-Doolittle Hydrophobicity Value -0.230
Molecular Weight (kDa) 66044.4
Isoelectric Point (pI) 6.11

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 101 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004136 (1240 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2715
Search term: lipoprotein

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268