Burkholderia pseudomallei K96243, BPSL2698 (groES)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2698
Name
groES
Replicon chromosome 1
Genomic location 3225167 - 3225460 (- strand)

Cross-References

RefSeq YP_109294.1
GI 53720308
Entrez 3094607
GI 53720308
INSDC CAH36706.1
NCBI Locus Tag BPSL2698
RefSeq YP_109294.1,GeneID
UniParc UPI0000127608
UniProtKB Acc Q63RH4
UniProtKB ID Q63RH4_BURPS
UniRef100 UniRef100_Q9ZFE1
UniRef50 UniRef50_P35474
UniRef90 UniRef90_Q8Y1P9

Product

Feature Type CDS
Coding Frame 1
Product Name
co-chaperonin GroES
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (14.9 kDa, pI 6.00, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (14.7 kDa, pI 4.97, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (13.8 kDa, pI 4.97, PMID:21960737)
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (14.9 kDa, pI 5.21, PMID:21960737)
Charge (pH 7) -0.77
Kyte-Doolittle Hydrophobicity Value -0.245
Molecular Weight (kDa) 10490.1
Isoelectric Point (pI) 5.90

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 593 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000714 (656 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2698
Search term: groES

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268