Burkholderia pseudomallei K96243, BPSL2608

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL2608
Name
Replicon chromosome 1
Genomic location 3128727 - 3129845 (- strand)

Cross-References

RefSeq YP_109204.1
GI 53720218
Entrez 3092683
GI 53720218
INSDC CAH36616.1
NCBI Locus Tag BPSL2608
RefSeq YP_109204.1,GeneID
UniParc UPI000043B450
UniProtKB Acc Q63RR3
UniProtKB ID Q63RR3_BURPS
UniRef100 UniRef100_Q3JPP8
UniRef50 UniRef50_Q8ZLF4
UniRef90 UniRef90_Q3JPP8

Product

Feature Type CDS
Coding Frame 1
Product Name
ABC transporter ATP-binding protein
Synonyms
Evidence for Translation
Charge (pH 7) 2.66
Kyte-Doolittle Hydrophobicity Value -0.126
Molecular Weight (kDa) 40618.5
Isoelectric Point (pI) 8.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000806 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL2608

Human Homologs

Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.4e-23
Percent Identity: 31.7
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.4e-23
Percent Identity: 31.7
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.4e-23
Percent Identity: 31.7
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.4e-23
Percent Identity: 31.7
Ensembl 97, assembly GRCh38.p12
ATP binding cassette subfamily B member 4 [Source:HGNC Symbol;Acc:HGNC:45]
E-value: 2.4e-23
Percent Identity: 31.7

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268