Burkholderia pseudomallei K96243, BPSL1907 (odhL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1907
Name
odhL
Replicon chromosome 1
Genomic location 2268814 - 2270244 (- strand)

Cross-References

RefSeq YP_108507.1
GI 53719521
Entrez 3094406
GI 53719521
INSDC CAH35907.1
NCBI Locus Tag BPSL1907
RefSeq YP_108507.1,GeneID
UniParc UPI000043B19E
UniProtKB Acc Q63TQ9
UniProtKB ID Q63TQ9_BURPS
UniRef100 UniRef100_A0A095KF93
UniRef50 UniRef50_P31052
UniRef90 UniRef90_I1WJP9

Product

Feature Type CDS
Coding Frame 1
Product Name
dihydrolipoamide dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -3.27
Kyte-Doolittle Hydrophobicity Value 0.017
Molecular Weight (kDa) 50358.6
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 646 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001338 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1907
Search term: odhL

Human Homologs

Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 1.7e-119
Percent Identity: 48.3
Ensembl 97, assembly GRCh38.p12
dihydrolipoamide dehydrogenase [Source:HGNC Symbol;Acc:HGNC:2898]
E-value: 1.7e-119
Percent Identity: 48.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268