Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSL1705
|
Name |
boaB
|
Replicon | chromosome 1 |
Genomic location | 1982643 - 1987463 (+ strand) |
RefSeq | YP_108306.1 |
GI | 53719320 |
Entrez | 3094881 |
GI | 53719320 |
NCBI Locus Tag | BPSL1705 |
RefSeq | YP_108306.1,GeneID |
UniProtKB Acc | Q63UB0 |
UniProtKB ID | Q63UB0_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
BoaB
|
Synonyms |
hypothetical protein |
Evidence for Translation | |
Charge (pH 7) | -19.90 |
Kyte-Doolittle Hydrophobicity Value | 0.154 |
Molecular Weight (kDa) | 148819.0 |
Isoelectric Point (pI) | 4.03 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | BGD |
Category | Trimeric autotransporter |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | boaB mutation has reduced net intracellular replication in J774.2 murine macrophage-like cells |
Reference | 25830295 |
Source 2 | |
Database | VFDB : VF0435 |
Category | Burkholderia oligomeric coiled-coil adhesin B |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Source 3 | |
Database | Victors : 2016 |
Category | |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Mus musculus |
Notes | boaB (BPSL1705) mutant has reduced attachment to respiratory cells, and a boaA boaB double mutant was attenuated in murine macrophages |
Reference | 16988221 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 81 genera
|
Burkholderia Ortholog Group |
BG002926 (1913 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSL1705
Search term: boaB
Search term: BoaB
|
Acid peptic disease.
J Assoc Physicians India 1990 Sep;38 Suppl 1:683-751
PubMed ID: 2092018
|
Systematic mutagenesis of genes encoding predicted autotransported proteins of Burkholderia pseudomallei identifies factors mediating virulence in mice, net intracellular replication and a novel protein conferring serum resistance.
Lazar Adler NR, Stevens MP, Dean RE, Saint RJ, Pankhania D, Prior JL, Atkins TP, Kessler B, Nithichanon A, Lertmemongkolchai G, Galyov EE
PLoS One 2015;10(4):e0121271
PubMed ID: 25830295
|