Burkholderia pseudomallei K96243, BPSL1504

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL1504
Name
Replicon chromosome 1
Genomic location 1742291 - 1743187 (+ strand)

Cross-References

RefSeq YP_108124.1
GI 53719138
Entrez 3092559
GI 53719138
INSDC CAH35505.1
NCBI Locus Tag BPSL1504
RefSeq YP_108124.1,GeneID
UniParc UPI000043B022
UniProtKB Acc Q63UU2
UniProtKB ID Q63UU2_BURPS
UniRef100 UniRef100_I1WII2
UniRef50 UniRef50_Q1LLI1
UniRef90 UniRef90_I1WII2

Product

Feature Type CDS
Coding Frame 1
Product Name
peptidase
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
Charge (pH 7) 7.64
Kyte-Doolittle Hydrophobicity Value -0.174
Molecular Weight (kDa) 30707.5
Isoelectric Point (pI) 9.77

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Extracellular Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 506 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001658 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1504
Search term: peptidase

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268