Burkholderia pseudomallei K96243, BPSL1405 (lon)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1405
Name
lon
Replicon chromosome 1
Genomic location 1634008 - 1636425 (+ strand)

Cross-References

RefSeq YP_108027.1
GI 53719041
Entrez 3092784
GI 53719041
INSDC CAH35406.1
NCBI Locus Tag BPSL1405
RefSeq YP_108027.1,GeneID
UniParc UPI000043AFC1
UniProtKB Acc Q63V39
UniProtKB ID Q63V39_BURPS
UniRef100 UniRef100_A0A069B8K4
UniRef50 UniRef50_P37945
UniRef90 UniRef90_B2JGL7

Product

Feature Type CDS
Coding Frame 1
Product Name
ATP-dependent protease
Synonyms
Evidence for Translation
Charge (pH 7) -4.67
Kyte-Doolittle Hydrophobicity Value -0.248
Molecular Weight (kDa) 89091.5
Isoelectric Point (pI) 6.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 569 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001785 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1405
Search term: lon

Human Homologs

Ensembl 86, assembly GRCh38.p7
lon peptidase 2, peroxisomal [Source:HGNC Symbol;Acc:HGNC:20598]
E-value: 9.6e-141
Percent Identity: 46.7

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268