Burkholderia pseudomallei K96243, BPSL1218 (nuoH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1218
Name
nuoH
Replicon chromosome 1
Genomic location 1403954 - 1405018 (+ strand)

Cross-References

RefSeq YP_107840.1
GI 53718854
Entrez 3091497
GI 53718854
INSDC CAH35213.1
NCBI Locus Tag BPSL1218
RefSeq YP_107840.1,GeneID
UniParc UPI000043AF06
UniProtKB Acc Q63VM6
UniProtKB ID NUOH_BURPS
UniRef100 UniRef100_Q62IP2
UniRef50 UniRef50_P92558
UniRef90 UniRef90_Q62IP2

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase subunit H
Synonyms
Evidence for Translation
Charge (pH 7) 4.12
Kyte-Doolittle Hydrophobicity Value 0.982
Molecular Weight (kDa) 39187.5
Isoelectric Point (pI) 8.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002129 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1218
Search term: nuoH

Human Homologs

Ensembl 86, assembly GRCh38.p7
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 [Source:HGNC Symbol;Acc:HGNC:7455]
E-value: 2.2e-57
Percent Identity: 41.3

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268