Burkholderia pseudomallei K96243, BPSL1218 (nuoH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1218
Name
nuoH
Replicon chromosome 1
Genomic location 1403954 - 1405018 (+ strand)

Cross-References

RefSeq YP_107840.1
GI 53718854
Entrez 3091497
GI 53718854
INSDC CAH35213.1
NCBI Locus Tag BPSL1218
RefSeq YP_107840.1,GeneID
UniParc UPI000043AF06
UniProtKB Acc Q63VM6
UniProtKB ID NUOH_BURPS
UniRef100 UniRef100_Q62IP2
UniRef50 UniRef50_P92558
UniRef90 UniRef90_Q62IP2

Product

Feature Type CDS
Coding Frame 1
Product Name
NADH dehydrogenase subunit H
Synonyms
Evidence for Translation
Charge (pH 7) 4.12
Kyte-Doolittle Hydrophobicity Value 0.982
Molecular Weight (kDa) 39187.5
Isoelectric Point (pI) 8.96

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 489 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002129 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1218
Search term: nuoH

Human Homologs

Ensembl 86, assembly GRCh38.p7
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 [Source:HGNC Symbol;Acc:HGNC:7455]
E-value: 2.2e-57
Percent Identity: 41.3

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268