Burkholderia pseudomallei K96243, BPSL1207 (pnp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1207
Name
pnp
Replicon chromosome 1
Genomic location 1391849 - 1393990 (+ strand)

Cross-References

RefSeq YP_107829.1
GI 53718843
Entrez 3092633
GI 53718843
INSDC CAH35202.1
NCBI Locus Tag BPSL1207
RefSeq YP_107829.1,GeneID
UniParc UPI000043AEFB
UniProtKB Acc Q63VN7
UniProtKB ID PNP_BURPS
UniRef100 UniRef100_A3NTA2
UniRef50 UniRef50_P41121
UniRef90 UniRef90_Q142H7

Product

Feature Type CDS
Coding Frame 1
Product Name
polynucleotide phosphorylase
Synonyms
Evidence for Translation
Charge (pH 7) -15.90
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 76989.5
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002140 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1207
Search term: pnp

Human Homologs

Ensembl 86, assembly GRCh38.p7
polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166]
E-value: 9.2e-119
Percent Identity: 37.8

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268