Burkholderia pseudomallei K96243, BPSL1207 (pnp)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSL1207
Name
pnp
Replicon chromosome 1
Genomic location 1391849 - 1393990 (+ strand)

Cross-References

RefSeq YP_107829.1
GI 53718843
Entrez 3092633
GI 53718843
INSDC CAH35202.1
NCBI Locus Tag BPSL1207
RefSeq YP_107829.1,GeneID
UniParc UPI000043AEFB
UniProtKB Acc Q63VN7
UniProtKB ID PNP_BURPS
UniRef100 UniRef100_A3NTA2
UniRef50 UniRef50_P41121
UniRef90 UniRef90_Q142H7

Product

Feature Type CDS
Coding Frame 1
Product Name
polynucleotide phosphorylase
Synonyms
Evidence for Translation
Charge (pH 7) -15.90
Kyte-Doolittle Hydrophobicity Value -0.117
Molecular Weight (kDa) 76989.5
Isoelectric Point (pI) 5.18

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 641 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002140 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL1207
Search term: pnp

Human Homologs

Ensembl 86, assembly GRCh38.p7
polyribonucleotide nucleotidyltransferase 1 [Source:HGNC Symbol;Acc:HGNC:23166]
E-value: 9.2e-119
Percent Identity: 37.8

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268