Burkholderia pseudomallei K96243, BPSL0688 (glpD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0688
Name
glpD
Replicon chromosome 1
Genomic location 784486 - 786018 (- strand)

Cross-References

RefSeq YP_107317.1
GI 53718331
Entrez 3093043
GI 53718331
INSDC CAH34681.1
NCBI Locus Tag BPSL0688
RefSeq YP_107317.1,GeneID
UniParc UPI000043AD00
UniProtKB Acc Q63X49
UniProtKB ID Q63X49_BURPS
UniRef100 UniRef100_Q3JVT3
UniRef50 UniRef50_P13035
UniRef90 UniRef90_A1V6Z8

Product

Feature Type CDS
Coding Frame 1
Product Name
glycerol-3-phosphate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) 9.50
Kyte-Doolittle Hydrophobicity Value -0.265
Molecular Weight (kDa) 56443.6
Isoelectric Point (pI) 9.16

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 378 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002536 (651 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0688
Search term: glpD

Human Homologs

Ensembl 97, assembly GRCh38.p12
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.8e-42
Percent Identity: 29.1
Ensembl 97, assembly GRCh38.p12
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.8e-42
Percent Identity: 29.1
Ensembl 97, assembly GRCh38.p12
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.8e-42
Percent Identity: 29.1
Ensembl 97, assembly GRCh38.p12
glycerol-3-phosphate dehydrogenase 2 [Source:HGNC Symbol;Acc:HGNC:4456]
E-value: 1.8e-42
Percent Identity: 29.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268