Burkholderia pseudomallei K96243, BPSL0513

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0513
Name
Replicon chromosome 1
Genomic location 567360 - 568004 (+ strand)

Cross-References

RefSeq YP_107139.1
GI 53718153
Entrez 3092068
GI 53718153
INSDC CAH34503.1
NCBI Locus Tag BPSL0513
RefSeq YP_107139.1,GeneID
UniParc UPI000043AC4E
UniProtKB Acc Q63XM6
UniProtKB ID Q63XM6_BURPS
UniRef100 UniRef100_A0A069AY76
UniRef50 UniRef50_Q9KSB2
UniRef90 UniRef90_A3N5J2

Product

Feature Type CDS
Coding Frame 1
Product Name
maleylacetoacetate isomerase
Synonyms
Evidence for Translation
Charge (pH 7) -1.42
Kyte-Doolittle Hydrophobicity Value -0.143
Molecular Weight (kDa) 24049.3
Isoelectric Point (pI) 6.63

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 215 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002661 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0513

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutathione S-transferase zeta 1 [Source:HGNC Symbol;Acc:HGNC:4643]
E-value: 1.4e-44
Percent Identity: 47.1
Ensembl 97, assembly GRCh38.p12
glutathione S-transferase zeta 1 [Source:HGNC Symbol;Acc:HGNC:4643]
E-value: 1.4e-44
Percent Identity: 47.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268