Burkholderia pseudomallei K96243, BPSL0400 (cpdB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0400
Name
cpdB
Replicon chromosome 1
Genomic location 433552 - 435612 (- strand)

Cross-References

RefSeq YP_107026.1
GI 53718040
Entrez 3091766
GI 53718040
INSDC CAH34388.1
NCBI Locus Tag BPSL0400
RefSeq YP_107026.1,GeneID
UniParc UPI000043ABDE
UniProtKB Acc Q63XY9
UniProtKB ID Q63XY9_BURPS
UniRef100 UniRef100_A3NQW1
UniRef50 UniRef50_A3RZL0
UniRef90 UniRef90_A1V031

Product

Feature Type CDS
Coding Frame 1
Product Name
2',3'-cyclic-nucleotide 2'-phosphodiesterase
Synonyms
Evidence for Translation
Charge (pH 7) 1.80
Kyte-Doolittle Hydrophobicity Value -0.090
Molecular Weight (kDa) 72860.7
Isoelectric Point (pI) 7.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 290 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002742 (633 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0400
Search term: cpdB

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268