Burkholderia pseudomallei K96243, BPSL0372

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0372
Name
Replicon chromosome 1
Genomic location 401445 - 402215 (- strand)

Cross-References

RefSeq YP_106998.1
GI 53718012
Entrez 3092418
GI 53718012
INSDC CAH34360.1
NCBI Locus Tag BPSL0372
RefSeq YP_106998.1,GeneID
UniParc UPI000043ABC2
UniProtKB Acc Q63Y17
UniProtKB ID Q63Y17_BURPS
UniRef100 UniRef100_A0A069AXA0
UniRef50 UniRef50_Q8PAC9
UniRef90 UniRef90_Q2T1P6

Product

Feature Type CDS
Coding Frame 1
Product Name
carbonic anhydrase
Synonyms
Evidence for Translation
Charge (pH 7) -1.55
Kyte-Doolittle Hydrophobicity Value -0.151
Molecular Weight (kDa) 28229.8
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 374 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002767 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0372

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268