Burkholderia pseudomallei K96243, BPSL0224

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0224
Name
Replicon chromosome 1
Genomic location 233741 - 235384 (+ strand)

Cross-References

RefSeq YP_106852.1
GI 53717866
Entrez 3092388
GI 53717866
INSDC CAH34212.1
NCBI Locus Tag BPSL0224
RefSeq YP_106852.1,GeneID
UniParc UPI000043AB33
UniProtKB Acc Q63YG3
UniProtKB ID Q63YG3_BURPS
UniRef100 UniRef100_A0A097XV15
UniRef50 UniRef50_A9ABT4
UniRef90 UniRef90_Q2T247

Product

Feature Type CDS
Coding Frame 1
Product Name
GMC oxidoreductase
Synonyms
Evidence for Translation
Charge (pH 7) 3.83
Kyte-Doolittle Hydrophobicity Value -0.154
Molecular Weight (kDa) 58702.0
Isoelectric Point (pI) 7.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 213 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002895 (649 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0224

Human Homologs

Ensembl 97, assembly GRCh38.p12
choline dehydrogenase [Source:HGNC Symbol;Acc:HGNC:24288]
E-value: 2.7e-108
Percent Identity: 42.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268