Burkholderia pseudomallei K96243, BPSL0188 (gatA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0188
Name
gatA
Replicon chromosome 1
Genomic location 193633 - 195123 (+ strand)

Cross-References

RefSeq YP_106816.1
GI 53717830
Entrez 3094691
GI 53717830
INSDC CAH34175.1
NCBI Locus Tag BPSL0188
RefSeq YP_106816.1,GeneID
UniParc UPI000043AB0F
UniProtKB Acc Q63YJ9
UniProtKB ID GATA_BURPS
UniRef100 UniRef100_A3NQ45
UniRef50 UniRef50_O06491
UniRef90 UniRef90_A3MNR6

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartyl/glutamyl-tRNA amidotransferase subunit A
Synonyms
Evidence for Translation
Charge (pH 7) -3.19
Kyte-Doolittle Hydrophobicity Value -0.054
Molecular Weight (kDa) 52235.5
Isoelectric Point (pI) 6.33

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002936 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0188
Search term: gatA

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutaminyl-tRNA amidotransferase subunit QRSL1 [Source:HGNC Symbol;Acc:HGNC:21020]
E-value: 3.0e-82
Percent Identity: 38.1

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268