Burkholderia cenocepacia K56-2, WQ49_RS11495 (paaF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2
Locus Tag
WQ49_RS11495
NCBI Old Locus TagWQ49_11500
Name
paaF
Replicon scf7180000000051
Genomic location 3442 - 4218 (- strand)

Cross-References

RefSeq WP_006491102.1
GI 493537172
NCBI Locus Tag WQ49_RS11495
NCBI Old Locus Tag WQ49_11500
RefSeq WP_006491102.1

Product

Feature Type CDS
Coding Frame 1
Product Name
PaaF
Product Name Confidence: Class 2
Synonyms enoyl-CoA hydratase
Evidence for Translation
Charge (pH 7) -3.37
Kyte-Doolittle Hydrophobicity Value 0.074
Molecular Weight (kDa) 27995.1
Isoelectric Point (pI) 5.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000434 (657 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: WQ49_RS11495
Search term: paaF
Search term: PaaF

Human Homologs

Ensembl 86, assembly GRCh38.p7
enoyl-CoA hydratase, short chain 1 [Source:HGNC Symbol;Acc:HGNC:3151]
E-value: 4.3e-74
Percent Identity: 56.4

References

A functional phenylacetic acid catabolic pathway is required for full pathogenicity of Burkholderia cenocepacia in the Caenorhabditis elegans host model.
Law RJ(1), Hamlin JN, Sivro A, McCorrister SJ, Cardama GA, Cardona ST.
J Bacteriol. 2008 Nov;190(21):7209-18.
PubMed ID: 18776009
PubMed ID: 20660314