Burkholderia lata 383, BCEP18194_RS34115 (bceA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia lata 383
GCF_000012945.1|latest
Locus Tag
BCEP18194_RS34115
NCBI Old Locus TagBcep18194_B2277
Name
bceA
Synonym: cpsB
Replicon chromosome 2
Genomic location 2601393 - 2602919 (+ strand)
CommentMember of the bce-I gene cluster

Cross-References

RefSeq WP_011355870.1
GI 499675136
NCBI Locus Tag BCEP18194_RS34115
NCBI Old Locus Tag Bcep18194_B2277
RefSeq WP_011355870.1

Product

Feature Type CDS
Coding Frame NA
Product Name
BceA
Product Name Confidence: Class 2
Synonyms mannose-1-phosphate guanylyltransferase
Evidence for Translation
Charge (pH 7) -7.32
Kyte-Doolittle Hydrophobicity Value -0.116
Molecular Weight (kDa) 55199.3
Isoelectric Point (pI) 6.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003312 (1226 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCEP18194_RS34115
Search term: bceA
Search term: BceA

Human Homologs

References

Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863
The Burkholderia cepacia bceA gene encodes a protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Wopperer J, Eberl L, Sá-Correia I, Leitão JH
Biochem Biophys Res Commun 2007 Feb 2;353(1):200-6
PubMed ID: 17184737
Functional analysis of the Burkholderia cenocepacia J2315 BceAJ protein with phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities.
Sousa SA, Moreira LM, Leitão JH
Appl Microbiol Biotechnol 2008 Oct;80(6):1015-22
PubMed ID: 18668237