Burkholderia lata 383, BCEP18194_RS17050 (lpxH)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia lata 383
GCF_000012945.1|latest |
| Locus Tag |
BCEP18194_RS17050
|
| NCBI Old Locus Tag | Bcep18194_A5388 |
| Name |
lpxH
|
| Replicon | chromosome 1 |
| Genomic location | 2454155 - 2454955 (+ strand) |
Cross-References
| RefSeq | WP_011352519.1 |
| GI | 499671785 |
| NCBI Locus Tag | BCEP18194_RS17050 |
| NCBI Old Locus Tag | Bcep18194_A5388 |
| RefSeq | WP_011352519.1 |
Product
| Feature Type | CDS |
| Coding Frame | NA |
| Product Name |
UDP-2,3-diacylglucosamine hydrolase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | 6.61 |
| Kyte-Doolittle Hydrophobicity Value | -0.197 |
| Molecular Weight (kDa) | 30090.2 |
| Isoelectric Point (pI) | 9.64 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG001974 (654 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BCEP18194_RS17050
Search term: lpxH
Search term: UDP-2,3-diacylglucosamine hydrolase
|
Human Homologs
References
|
The LpxL acyltransferase is required for normal growth and penta-acylation of lipid A in Burkholderia cenocepacia.
Fathy Mohamed Y, Hamad M, Ortega XP, Valvano MA
Mol Microbiol 2017 Apr;104(1):144-162
PubMed ID: 28085228
|