Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS21450 (lpxB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS21450
NCBI Old Locus TagBURCENK562V_C1113
Name
lpxB
Replicon ctg7180000002937
Genomic location 278152 - 279321 (+ strand)

Cross-References

RefSeq WP_006483810.1
GI 493529795
EC Number 2.4.1.182
GI 493529795
NCBI Locus Tag BURCENK562V_RS21450
NCBI Old Locus Tag BURCENK562V_C1113
RefSeq WP_006483810.1

Product

Feature Type CDS
Coding Frame 1
Product Name
lipid-A-disaccharide synthase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 3.87
Kyte-Doolittle Hydrophobicity Value 0.064
Molecular Weight (kDa) 42344.8
Isoelectric Point (pI) 8.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001896 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: lpxB

Human Homologs

References

Complete structural characterization of the lipid A fraction of a clinical strain of B. cepacia genomovar I lipopolysaccharide.
Silipo A, Molinaro A, Cescutti P, Bedini E, Rizzo R, Parrilli M, Lanzetta R
Glycobiology 2005 May;15(5):561-70
PubMed ID: 15610978