Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS28260 (tssG)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest |
| Locus Tag |
BURCENK562V_RS28260
|
| NCBI Old Locus Tag | BURCENK562V_C6653 |
| Name |
tssG
Synonym: bcsG |
| Replicon | ctg7180000002941 |
| Genomic location | 450956 - 452056 (+ strand) |
| Comment | Part of the T6SS gene cluster |
Cross-References
| RefSeq | WP_006484394.1 |
| GI | 493530382 |
| GI | 493530382 |
| NCBI Locus Tag | BURCENK562V_RS28260 |
| NCBI Old Locus Tag | BURCENK562V_C6653 |
| RefSeq | WP_006484394.1 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
type VI secretion system protein TssG
|
| Synonyms |
type VI secretion protein |
| Evidence for Translation | |
| Charge (pH 7) | -5.09 |
| Kyte-Doolittle Hydrophobicity Value | -0.093 |
| Molecular Weight (kDa) | 40293.3 |
| Isoelectric Point (pI) | 5.90 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG000371 (648 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BURCENK562V_RS28260
Search term: tssG
Search term: type VI secretion system protein TssG
|
Human Homologs
References
|
A novel sensor kinase-response regulator hybrid controls biofilm formation and type VI secretion system activity in Burkholderia cenocepacia.
Aubert DF, Flannagan RS, Valvano MA
Infect Immun 2008 May;76(5):1979-91
PubMed ID: 18316384
|
|
TssK is a trimeric cytoplasmic protein interacting with components of both phage-like and membrane anchoring complexes of the type VI secretion system.
Zoued A, Durand E, Bebeacua C, Brunet YR, Douzi B, Cambillau C, Cascales E, Journet L
J Biol Chem 2013 Sep 20;288(38):27031-41
PubMed ID: 23921384
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Quantification of type VI secretion system activity in macrophages infected with Burkholderia cenocepacia.
Aubert DF, Hu S, Valvano MA
Microbiology 2015 Nov;161(11):2161-73
PubMed ID: 26364149
|