Burkholderia cenocepacia AU 1054, BCEN_RS11175 (gpmA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia AU 1054
GCF_000014085.1|latest
Locus Tag
BCEN_RS11175
NCBI Old Locus TagBcen_2243
Name
gpmA
Replicon chromosome 1
Genomic location 2471907 - 2472653 (+ strand)

Cross-References

RefSeq WP_012329275.1
GI 501286257
NCBI Locus Tag BCEN_RS11175
NCBI Old Locus Tag Bcen_2243
RefSeq WP_012329275.1

Product

Feature Type CDS
Coding Frame NA
Product Name
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase
Synonyms
Evidence for Translation
Charge (pH 7) -0.59
Kyte-Doolittle Hydrophobicity Value -0.394
Molecular Weight (kDa) 27924.5
Isoelectric Point (pI) 6.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3EZN ISOMERASE 10/23/08 Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b BURKHOLDERIA PSEUDOMALLEI 1710B 2.1 X-RAY DIFFRACTION 92.2
3LNT ISOMERASE 02/03/10 Crystal structure of phosphoglyceromutase from Burkholderia Pseudomallei 1710B with bound malonic acid BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 92.3
3GW8 ISOMERASE 03/31/09 Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with vanadate and glycerol BURKHOLDERIA PSEUDOMALLEI 1.93 X-RAY DIFFRACTION 92.2
3FDZ ISOMERASE 11/26/08 Crystal structure of phosphoglyceromutase from burkholderia pseudomallei 1710b with bound 2,3-diphosphoglyceric acid and 3-phosphoglyceric acid BURKHOLDERIA PSEUDOMALLEI 1710B 2.25 X-RAY DIFFRACTION 92.2
3GP5 ISOMERASE 03/20/09 Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with 3-phosphoglyceric acid and vanadate BURKHOLDERIA PSEUDOMALLEI 2.25 X-RAY DIFFRACTION 92.2
3GP3 ISOMERASE 03/20/09 Crystal structure of phosphoglyceromutase from Burkholderia pseudomallei with 2-phosphoserine BURKHOLDERIA PSEUDOMALLEI 1.5 X-RAY DIFFRACTION 92.2

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002703 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCEN_RS11175
Search term: gpmA

Human Homologs

Ensembl 97, assembly GRCh38.p12
phosphoglycerate mutase 1 [Source:HGNC Symbol;Acc:HGNC:8888]
E-value: 5.9e-87
Percent Identity: 61.1

References

No references are associated with this feature.