Burkholderia cenocepacia AU 1054, BCEN_RS10735

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia AU 1054
GCF_000014085.1|latest
Locus Tag
BCEN_RS10735
NCBI Old Locus TagBcen_2157
Name
Replicon chromosome 1
Genomic location 2382060 - 2382803 (- strand)

Cross-References

RefSeq WP_027809372.1
GI 654294734
NCBI Locus Tag BCEN_RS10735
NCBI Old Locus Tag Bcen_2157
RefSeq WP_027809372.1

Product

Feature Type CDS
Coding Frame NA
Product Name
acetoacetyl-CoA reductase
Synonyms
Evidence for Translation
Charge (pH 7) 2.55
Kyte-Doolittle Hydrophobicity Value -0.045
Molecular Weight (kDa) 26339.0
Isoelectric Point (pI) 8.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4K6C OXIDOREDUCTASE 04/15/13 X-ray crystal structure of a putative Acetoacyl-CoA reductase from Burkholderia cenocepacia BURKHOLDERIA CENOCEPACIA 1.85 X-RAY DIFFRACTION 99.2
4K6F OXIDOREDUCTASE 04/15/13 X-ray crystal structure of a putative Acetoacetyl-CoA reductase from Burkholderia cenocepacia bound to the co-factor NADP BURKHOLDERIA CENOCEPACIA 1.5 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002622 (851 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCEN_RS10735

Human Homologs

Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5
Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5
Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5
Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5
Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5
Ensembl 97, assembly GRCh38.p12
hydroxysteroid 17-beta dehydrogenase 8 [Source:HGNC Symbol;Acc:HGNC:3554]
E-value: 5.3e-35
Percent Identity: 35.5

References

No references are associated with this feature.