Burkholderia cenocepacia J2315, BCAS0608 (bktB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAS0608
NCBI Locus Tag	QU43_RS71695
Name	bktB
Replicon	chromosome 3
Genomic location	664532 - 665725 (- strand)

Cross-References

RefSeq	WP_006481441.1
GI	197295449
Entrez	6803981
GI	197295449
INSDC	CAR57540.1
NCBI Locus Tag	QU43_RS71695
NCBI Old Locus Tag	BCAS0608
RefSeq	WP_006481441.1,GeneID
UniParc	UPI000052EC88
UniProtKB Acc	B4EP02
UniProtKB ID	B4EP02_BURCJ
UniRef100	UniRef100_B4EP02
UniRef50	UniRef50_Q0KBP1
UniRef90	UniRef90_G7HRH5

Product

Feature Type	CDS
Coding Frame	1
Product Name	beta-ketothiolase
Synonyms
Evidence for Translation
Charge (pH 7)	-0.68
Kyte-Doolittle Hydrophobicity Value	0.102
Molecular Weight (kDa)	41042.5
Isoelectric Point (pI)	6.86

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 464 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG005018 (641 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAS0608 Search term: bktB Search term: beta-ketothiolase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000285093 acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] E-value: 8.9e-93 Percent Identity: 47.2
Ensembl 97, assembly GRCh38.p12	ENSP00000466015 acetyl-CoA acyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:83] E-value: 8.9e-93 Percent Identity: 47.2

References