Burkholderia cenocepacia J2315, BCAM2193 (mmsB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM2193
NCBI Locus Tag	QU43_RS65330
Name	mmsB
Replicon	chromosome 2
Genomic location	2451773 - 2452672 (- strand)

Cross-References

RefSeq	WP_006480765.1
GI	206564030
Entrez	6929781
GI	206564030
INSDC	CAR56051.1
NCBI Locus Tag	QU43_RS65330
NCBI Old Locus Tag	BCAM2193
RefSeq	WP_006480765.1,GeneID
UniParc	UPI000052E512
UniProtKB Acc	B4EGC5
UniProtKB ID	B4EGC5_BURCJ
UniRef100	UniRef100_B1K7Z9
UniRef50	UniRef50_Q9I5I6
UniRef90	UniRef90_A9ANK1

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative 3-hydroxyisobutyrate dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.66
Kyte-Doolittle Hydrophobicity Value	0.236
Molecular Weight (kDa)	30133.1
Isoelectric Point (pI)	6.51

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 466 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003928 (1248 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM2193 Search term: mmsB Search term: putative 3-hydroxyisobutyrate dehydrogenase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000265395 3-hydroxyisobutyrate dehydrogenase [Source:HGNC Symbol;Acc:HGNC:4907] E-value: 2.9e-80 Percent Identity: 52.3

References