Burkholderia cenocepacia J2315, BCAM0818

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0818
NCBI Locus TagQU43_RS58475
Name
Replicon chromosome 2
Genomic location 900994 - 902427 (+ strand)

Cross-References

RefSeq WP_006490987.1
GI 206562675
Entrez 6928574
GI 206562675
INSDC CAR54676.1
NCBI Locus Tag QU43_RS58475
NCBI Old Locus Tag BCAM0818
RefSeq WP_006490987.1,GeneID
UniParc UPI00017B9DDC
UniProtKB Acc B4EMM0
UniProtKB ID B4EMM0_BURCJ
UniRef100 UniRef100_A0A095EB61
UniRef50 UniRef50_W9VQ31
UniRef90 UniRef90_Q393E4

Product

Feature Type CDS
Coding Frame 1
Product Name
putative aldehyde dehydrogenase
Synonyms
Evidence for Translation
Charge (pH 7) -5.68
Kyte-Doolittle Hydrophobicity Value -0.111
Molecular Weight (kDa) 51926.7
Isoelectric Point (pI) 5.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5KF0 OXIDOREDUCTASE 06/10/16 Crystal structure of an Aldedhyde dehydrogenase from Burkholderia vietnamiensis BURKHOLDERIA VIETNAMIENSIS (STRAIN G4 / LMG 22486) 1.7 X-RAY DIFFRACTION 94.3
5JRY OXIDOREDUCTASE 05/06/16 Crystal structure of a NAD-dependent Aldehyde dehydrogenase from Burkholderia multivorans in covalent complex with NAD BURKHOLDERIA MULTIVORANS (STRAIN ATCC 17616 / 249) 1.2 X-RAY DIFFRACTION 94.5

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 595 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG004823 (648 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0818

Human Homologs

Ensembl 97, assembly GRCh38.p12
aldehyde dehydrogenase 5 family member A1 [Source:HGNC Symbol;Acc:HGNC:408]
E-value: 2.5e-57
Percent Identity: 33.1

References

No references are associated with this feature.