Burkholderia cenocepacia J2315, BCAM0333 (virB10)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0333
NCBI Locus TagQU43_RS56070
Name
virB10
Synonym: bcvirB10
Replicon chromosome 2
Genomic location 387072 - 388295 (+ strand)
CommentThis gene is part of the B. cenocepacia J2315 VirB-VirD-like type IV secretion system cluster.

Cross-References

RefSeq WP_006488449.1
GI 206562199
Entrez 6928122
GI 206562199
INSDC CAR54192.1
NCBI Locus Tag QU43_RS56070
NCBI Old Locus Tag BCAM0333
RefSeq WP_006488449.1,GeneID
UniParc UPI00017B9B31
UniProtKB Acc B4EIS4
UniProtKB ID B4EIS4_BURCJ
UniRef100 UniRef100_A0A0D1DCJ1
UniRef50 UniRef50_Q13XJ3
UniRef90 UniRef90_B1K7J3

Product

Feature Type CDS
Coding Frame 1
Product Name
putative type IV secretion system protein VirB10
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) -6.92
Kyte-Doolittle Hydrophobicity Value -0.169
Molecular Weight (kDa) 42816.5
Isoelectric Point (pI) 5.60

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 126 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001874 (68 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0333
Search term: virB10

Human Homologs

References

Involvement of a plasmid-encoded type IV secretion system in the plant tissue watersoaking phenotype of Burkholderia cenocepacia.
Engledow AS, Medrano EG, Mahenthiralingam E, LiPuma JJ, Gonzalez CF
J Bacteriol 2004 Sep;186(18):6015-24
PubMed ID: 15342570
Two type IV secretion systems with different functions in Burkholderia cenocepacia K56-2.
Zhang R, LiPuma JJ, Gonzalez CF
Microbiology 2009 Dec;155(Pt 12):4005-4013
PubMed ID: 19744991
A type IV secretion system contributes to intracellular survival and replication of Burkholderia cenocepacia.
Sajjan SU, Carmody LA, Gonzalez CF, LiPuma JJ
Infect Immun 2008 Dec;76(12):5447-55
PubMed ID: 18824538