Burkholderia cenocepacia J2315, BCAL3446 (pilC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3446
NCBI Locus Tag	QU43_RS53935
Name	pilC
Replicon	chromosome 1
Genomic location	3773996 - 3775201 (+ strand)

Cross-References

RefSeq	WP_006496766.1
GI	206561783
Entrez	6933221
GI	206561783
INSDC	CAR53769.1
NCBI Locus Tag	QU43_RS53935
NCBI Old Locus Tag	BCAL3446
RefSeq	WP_006496766.1,GeneID
UniParc	UPI00017B9E3C
UniProtKB Acc	B4E5X6
UniProtKB ID	B4E5X6_BURCJ
UniRef100	UniRef100_B4E5X6
UniRef50	UniRef50_B4E5X6
UniRef90	UniRef90_B4E5X6

Product

Feature Type	CDS
Coding Frame	1
Product Name	type IV pilus assembly protein PilC
Synonyms
Evidence for Translation
Charge (pH 7)	18.83
Kyte-Doolittle Hydrophobicity Value	0.400
Molecular Weight (kDa)	42260.7
Isoelectric Point (pI)	11.83

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database	VFDB : VF0431
Category	Type IV pili
Evidence	ECO:0000250 sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from	Burkholderia pseudomallei K96243
Reference	17984080

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 400 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000465 (649 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3446 Search term: pilC Search term: type IV pilus assembly protein PilC

Human Homologs

References