Burkholderia cenocepacia J2315, BCAL3373 (leuS)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3373
NCBI Locus Tag	QU43_RS53565
Name	leuS
Replicon	chromosome 1
Genomic location	3696455 - 3699049 (- strand)

Cross-References

RefSeq	WP_006483409.1
GI	206561710
Entrez	6933176
GI	206561710
INSDC	CAR53696.1
NCBI Locus Tag	QU43_RS53565
NCBI Old Locus Tag	BCAL3373
RefSeq	WP_006483409.1,GeneID
UniParc	UPI00017B9847
UniProtKB Acc	B4EEW1
UniProtKB ID	SYL_BURCJ
UniRef100	UniRef100_B4EEW1
UniRef50	UniRef50_Q087K2
UniRef90	UniRef90_Q2SZ91

Product

Feature Type	CDS
Coding Frame	1
Product Name	leucyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-16.61
Kyte-Doolittle Hydrophobicity Value	-0.283
Molecular Weight (kDa)	96212.0
Isoelectric Point (pI)	5.10

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 668 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000533 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3373 Search term: leuS Search term: leucyl-tRNA synthetase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000495707 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 1.9e-148 Percent Identity: 36.2
Ensembl 97, assembly GRCh38.p12	ENSP00000498867 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 1.9e-148 Percent Identity: 36.2
Ensembl 97, assembly GRCh38.p12	ENSP00000495093 leucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:17095] E-value: 1.9e-148 Percent Identity: 36.2

References