Burkholderia cenocepacia J2315, BCAL3370 (proA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3370
NCBI Locus Tag	QU43_RS53550
Name	proA
Replicon	chromosome 1
Genomic location	3693271 - 3694578 (- strand)

Cross-References

RefSeq	YP_002232472.1
GI	206561707
Entrez	6933174
GI	206561707
NCBI Locus Tag	QU43_RS53550
NCBI Old Locus Tag	BCAL3370
RefSeq	YP_002232472.1
UniProtKB Acc	B4EEV8
UniProtKB ID	B4EEV8_BURCJ

Product

Feature Type	CDS
Coding Frame	1
Product Name	gamma-glutamyl phosphate reductase
Synonyms
Evidence for Translation
Charge (pH 7)	-1.98
Kyte-Doolittle Hydrophobicity Value	-0.047
Molecular Weight (kDa)	46557.7
Isoelectric Point (pI)	6.71

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 515 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000536 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3370 Search term: proA Search term: gamma-glutamyl phosphate reductase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000360265 aldehyde dehydrogenase 18 family member A1 [Source:HGNC Symbol;Acc:HGNC:9722] E-value: 3.6e-63 Percent Identity: 39.7
Ensembl 97, assembly GRCh38.p12	ENSP00000360268 aldehyde dehydrogenase 18 family member A1 [Source:HGNC Symbol;Acc:HGNC:9722] E-value: 3.6e-63 Percent Identity: 39.7

References