Burkholderia cenocepacia J2315, BCAL3351 (pyrC)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3351
NCBI Locus Tag	QU43_RS53460
Name	pyrC
Replicon	chromosome 1
Genomic location	3668765 - 3669859 (- strand)

Cross-References

RefSeq	YP_002232455.1
GI	206561690
Entrez	6933164
GI	206561690
NCBI Locus Tag	QU43_RS53460
NCBI Old Locus Tag	BCAL3351
RefSeq	YP_002232455.1
UniProtKB Acc	B4EEU0
UniProtKB ID	B4EEU0_BURCJ

Product

Feature Type	CDS
Coding Frame	1
Product Name	dihydroorotase
Synonyms
Evidence for Translation
Charge (pH 7)	-3.02
Kyte-Doolittle Hydrophobicity Value	-0.124
Molecular Weight (kDa)	39737.9
Isoelectric Point (pI)	6.57

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession	Header	Accession Date	Compound	Source	Resolution	Method	Percent Identity
4LFY	HYDROLASE	06/27/13	Crystal structure of a dihydroorotase from Burkholderia cenocepacia J2315	BURKHOLDERIA CENOCEPACIA	1.8	X-RAY DIFFRACTION	100.0

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 199 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000554 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3351 Search term: pyrC Search term: dihydroorotase

Human Homologs

References