Burkholderia cenocepacia J2315, BCAL3220 (wcbR)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3220
NCBI Locus Tag	QU43_RS52835
Name	wcbR
Replicon	chromosome 1
Genomic location	3514338 - 3521987 (- strand)

Cross-References

RefSeq	WP_006484972.1
GI	206561566
Entrez	6934255
GI	206561566
INSDC	CAR53546.1
NCBI Locus Tag	QU43_RS52835
NCBI Old Locus Tag	BCAL3220
RefSeq	WP_006484972.1,GeneID
UniParc	UPI00017B9808
UniProtKB Acc	B4EDD9
UniProtKB ID	B4EDD9_BURCJ
UniRef100	UniRef100_B4EDD9
UniRef50	UniRef50_Q39J94
UniRef90	UniRef90_Q39J94

Product

Feature Type	CDS
Coding Frame	1
Product Name	capsular polysaccharide biosynthesis fatty acid synthase
Synonyms
Evidence for Translation
Charge (pH 7)	-48.93
Kyte-Doolittle Hydrophobicity Value	0.099
Molecular Weight (kDa)	268606.8
Isoelectric Point (pI)	5.68

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Membrane Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database	VFDB : VF0436
Category	Type I O-polysaccharide
Evidence	ECO:0000250 sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from	Burkholderia pseudomallei K96243
Reference	17984080

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 611 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001460 (2297 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3220 Search term: wcbR Search term: capsular polysaccharide biosynthesis fatty acid synthase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000304592 fatty acid synthase [Source:HGNC Symbol;Acc:HGNC:3594] E-value: 2.2e-176 Percent Identity: 28.3

References