Burkholderia cenocepacia J2315, BCAL2908 (fumC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2908
NCBI Locus TagQU43_RS51185
Name
fumC
Replicon chromosome 1
Genomic location 3187061 - 3188455 (+ strand)

Cross-References

RefSeq WP_006486188.1
GI 206561243
Entrez 6933874
GI 206561243
INSDC CAR53207.1
NCBI Locus Tag QU43_RS51185
NCBI Old Locus Tag BCAL2908
RefSeq WP_006486188.1,GeneID
UniParc UPI00017B96B1
UniProtKB Acc B4EAL6
UniProtKB ID B4EAL6_BURCJ
UniRef100 UniRef100_B4EAL6
UniRef50 UniRef50_P05042
UniRef90 UniRef90_C5AD60

Product

Feature Type CDS
Coding Frame 1
Product Name
fumarate hydratase
Synonyms
Evidence for Translation
Charge (pH 7) -3.50
Kyte-Doolittle Hydrophobicity Value -0.048
Molecular Weight (kDa) 49712.2
Isoelectric Point (pI) 6.57

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3TV2 LYASE 09/19/11 Structure of a class II fumarate hydratase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.1 X-RAY DIFFRACTION 90.6

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 597 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000932 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2908
Search term: fumC

Human Homologs

Ensembl 97, assembly GRCh38.p12
fumarate hydratase [Source:HGNC Symbol;Acc:HGNC:3700]
E-value: 1.2e-160
Percent Identity: 63.0

References

No references are associated with this feature.