Burkholderia cenocepacia J2315, BCAL2730 (clpA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2730
NCBI Locus Tag	QU43_RS50265
Name	clpA
Replicon	chromosome 1
Genomic location	2997302 - 2999602 (- strand)

Cross-References

RefSeq	WP_006488947.1
GI	206561068
Entrez	6932748
GI	206561068
INSDC	CAR53031.1
NCBI Locus Tag	QU43_RS50265
NCBI Old Locus Tag	BCAL2730
RefSeq	WP_006488947.1,GeneID
UniParc	UPI00017B9829
UniProtKB Acc	B4E903
UniProtKB ID	B4E903_BURCJ
UniRef100	UniRef100_A0A0D1D7S3
UniRef50	UniRef50_P0ABI1
UniRef90	UniRef90_Q3JV78

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative ATP-dependent Clp protease ATP-binding subunit
Synonyms
Evidence for Translation
Charge (pH 7)	-6.01
Kyte-Doolittle Hydrophobicity Value	-0.251
Molecular Weight (kDa)	84472.8
Isoelectric Point (pI)	6.48

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 605 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002384 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2730 Search term: clpA Search term: putative ATP-dependent Clp protease ATP-binding subunit

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000407296 ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664] E-value: 1.3e-36 Percent Identity: 29.2
Ensembl 97, assembly GRCh38.p12	ENSP00000340385 ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664] E-value: 1.3e-36 Percent Identity: 29.2
Ensembl 97, assembly GRCh38.p12	ENSP00000294053 ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664] E-value: 1.3e-36 Percent Identity: 29.2
Ensembl 97, assembly GRCh38.p12	ENSP00000441518 ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664] E-value: 1.3e-36 Percent Identity: 29.2
Ensembl 97, assembly GRCh38.p12	ENSP00000443822 ClpB homolog, mitochondrial AAA ATPase chaperonin [Source:HGNC Symbol;Acc:HGNC:30664] E-value: 1.3e-36 Percent Identity: 29.2

References