Burkholderia cenocepacia J2315, BCAL2406 (wabR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2406
NCBI Locus TagQU43_RS48695
Name
wabR
Replicon chromosome 1
Genomic location 2661677 - 2662807 (- strand)

Cross-References

RefSeq WP_012492744.1
GI 206560765
Entrez 6932478
GI 206560765
INSDC CAR52707.1
NCBI Locus Tag QU43_RS48695
NCBI Old Locus Tag BCAL2406
RefSeq WP_012492744.1,GeneID
UniParc UPI00017B985C
UniProtKB Acc B4E6D2
UniProtKB ID B4E6D2_BURCJ
UniRef100 UniRef100_A0A095EQF4
UniRef50 UniRef50_A1V2D4
UniRef90 UniRef90_G7HKJ7

Product

Feature Type CDS
Coding Frame 1
Product Name
putative glycosyltransferase
Product Name Confidence: Class 1
Synonyms wabR
Evidence for Translation
Charge (pH 7) 16.14
Kyte-Doolittle Hydrophobicity Value -0.030
Molecular Weight (kDa) 41166.2
Isoelectric Point (pI) 9.94

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 236 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002196 (1008 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2406
Search term: wabR

Human Homologs

References

Biosynthesis and structure of the Burkholderia cenocepacia K56-2 lipopolysaccharide core oligosaccharide: truncation of the core oligosaccharide leads to increased binding and sensitivity to polymyxin B.
Ortega X, Silipo A, Saldías MS, Bates CC, Molinaro A, Valvano MA
J Biol Chem 2009 Aug 7;284(32):21738-51
PubMed ID: 19525227