Burkholderia cenocepacia J2315, BCAL2354 (leuA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2354
NCBI Locus Tag	QU43_RS48425
Name	leuA
Replicon	chromosome 1
Genomic location	2607793 - 2609337 (- strand)

Cross-References

RefSeq	WP_006491031.1
GI	206560713
Entrez	6932442
GI	206560713
INSDC	CAR52655.1
NCBI Locus Tag	QU43_RS48425
NCBI Old Locus Tag	BCAL2354
RefSeq	WP_006491031.1,GeneID
UniParc	UPI00017B97A7
UniProtKB Acc	B4E5N2
UniProtKB ID	LEU1_BURCJ
UniRef100	UniRef100_B4E5N2
UniRef50	UniRef50_P48575
UniRef90	UniRef90_B2JDN6

Product

Feature Type	CDS
Coding Frame	1
Product Name	2-isopropylmalate synthase
Synonyms
Evidence for Translation
Charge (pH 7)	-8.92
Kyte-Doolittle Hydrophobicity Value	-0.208
Molecular Weight (kDa)	55551.3
Isoelectric Point (pI)	5.42

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 581 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002146 (638 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2354 Search term: leuA Search term: 2-isopropylmalate synthase

Human Homologs

References