Burkholderia cenocepacia J2315, BCAL2198 (iscS)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2198
NCBI Locus Tag	QU43_RS47600
Name	iscS
Replicon	chromosome 1
Genomic location	2425456 - 2426679 (- strand)

Cross-References

RefSeq	WP_006481979.1
GI	206560560
Entrez	6932319
GI	206560560
INSDC	CAR52499.1
NCBI Locus Tag	QU43_RS47600
NCBI Old Locus Tag	BCAL2198
RefSeq	WP_006481979.1,GeneID
UniParc	UPI00017B93E6
UniProtKB Acc	B4EDS7
UniProtKB ID	B4EDS7_BURCJ
UniRef100	UniRef100_B4EDS7
UniRef50	UniRef50_Q486Z0
UniRef90	UniRef90_A1V5M6

Product

Feature Type	CDS
Coding Frame	1
Product Name	cysteine desulfurase
Synonyms
Evidence for Translation
Charge (pH 7)	-9.46
Kyte-Doolittle Hydrophobicity Value	-0.273
Molecular Weight (kDa)	45453.3
Isoelectric Point (pI)	5.87

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 653 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002019 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2198 Search term: iscS Search term: cysteine desulfurase

Human Homologs

Ensembl 97, assembly GRCh38.p12

ENSP00000363205 NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:HGNC:15910] E-value: 9.6e-143 Percent Identity: 59.5

References