Burkholderia cenocepacia J2315, BCAL2118 (aceA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2118
NCBI Locus TagQU43_RS47155
Name
aceA
Replicon chromosome 1
Genomic location 2334626 - 2335933 (+ strand)

Cross-References

RefSeq WP_006481952.1
GI 206560481
Entrez 6932262
GI 206560481
INSDC CAR52419.1
NCBI Locus Tag QU43_RS47155
NCBI Old Locus Tag BCAL2118
RefSeq WP_006481952.1,GeneID
UniParc UPI00017B939A
UniProtKB Acc B4ECQ9
UniProtKB ID B4ECQ9_BURCJ
UniRef100 UniRef100_B4ECQ9
UniRef50 UniRef50_A1V5A1
UniRef90 UniRef90_A1V5A1

Product

Feature Type CDS
Coding Frame 1
Product Name
isocitrate lyase
Synonyms
Evidence for Translation
Charge (pH 7) -5.15
Kyte-Doolittle Hydrophobicity Value -0.302
Molecular Weight (kDa) 47741.7
Isoelectric Point (pI) 5.92

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3I4E LYASE 07/01/09 Crystal structure of Isocitrate Lyase from Burkholderia pseudomallei BURKHOLDERIA PSEUDOMALLEI 2.69 X-RAY DIFFRACTION 97.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 314 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG001937 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2118
Search term: aceA
Search term: isocitrate lyase

Human Homologs

References

No references are associated with this feature.